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Identification of key amino acids responsible for the distinct aggregation properties of microtubule‐associated protein 2 and tau

The carboxyl‐terminal sequence of tau composes the framework for its intracellular inclusions that appear in diverse neurodegenerative disorders known as tauopathies. However, microtubule‐associated protein 2 (MAP2), which contains a homologous carboxyl‐terminal sequence of tau, is undetectable in t...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurochem
Hauptverfasser: Xie, Ce, Soeda, Yoshiyuki, Shinzaki, Yuki, In, Yasuko, Tomoo, Koji, Ihara, Yasuo, Miyasaka, Tomohiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049617/
https://ncbi.nlm.nih.gov/pubmed/26134402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13228
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