Neonatal T Helper 17 Responses Are Skewed Towards an Immunoregulatory Interleukin-22 Phenotype

Newborns are frequently affected by mucocutaneous candidiasis. Th17 cells essentially limit mucosal invasion by commensal Candida spp. Here, we sought to understand the molecular basis for the developmental lack of Th17 cell responses in circulating blood neonatal T cells. Naive cord blood CD4 T cel...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Razzaghian, Hamid R., Sharafian, Zohreh, Sharma, Ashish A., Boyce, Guilaine K., Lee, Kelsey, Da Silva, Rachel, Orban, Paul C., Sekaly, Rafick-Pierre, Ross, Colin J., Lavoie, Pascal M.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126652/
https://ncbi.nlm.nih.gov/pubmed/34012439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.655027
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