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Pathogenic T helper type 17 cells contribute to type 1 diabetes independently of interleukin‐22
We have shown that pathogenic T helper type 17 (Th17) cells differentiated from naive CD4(+) T cells of BDC2·5 T cell receptor transgenic non‐obese diabetic (NOD) mice by interleukin (IL)‐23 plus IL‐6 produce IL‐17, IL‐22 and induce type 1 diabetes (T1D). Neutralizing interferon (IFN)‐γ during the p...
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| Publicado no: | Clin Exp Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4750601/ https://ncbi.nlm.nih.gov/pubmed/26496462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12735 |
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