Pathogenic T helper type 17 cells contribute to type 1 diabetes independently of interleukin‐22

We have shown that pathogenic T helper type 17 (Th17) cells differentiated from naive CD4(+) T cells of BDC2·5 T cell receptor transgenic non‐obese diabetic (NOD) mice by interleukin (IL)‐23 plus IL‐6 produce IL‐17, IL‐22 and induce type 1 diabetes (T1D). Neutralizing interferon (IFN)‐γ during the p...

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Dades bibliogràfiques
Publicat a:Clin Exp Immunol
Autors principals: Bellemore, S. M., Nikoopour, E., Krougly, O., Lee‐Chan, E., Fouser, L. A., Singh, B.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750601/
https://ncbi.nlm.nih.gov/pubmed/26496462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12735
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