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Preventative role of interleukin-17 producing regulatory T helper type 17 (T(reg)17) cells in type 1 diabetes in non-obese diabetic mice

T helper type 17 (Th17) cells have been shown to be pathogenic in autoimmune diseases; however, their role in type 1 diabetes (T1D) remains inconclusive. We have found that Th17 differentiation of CD4(+) T cells from BDC2·5 T cell receptor transgenic non-obese diabetic (NOD) mice can be driven by in...

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Bibliografiska uppgifter
I publikationen:Clin Exp Immunol
Huvudupphovsmän: Bellemore, S M, Nikoopour, E, Schwartz, J A, Krougly, O, Lee-Chan, E, Singh, B
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons, Ltd 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636888/
https://ncbi.nlm.nih.gov/pubmed/26250153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12691
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