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The evolution of STING signaling and its implication in cancer

The cGAS-STING pathway has been primarily characterized as an inflammatory response mechanism in higher eukaryotes in response to the presence of cytosolic double-stranded DNA. Since its initial discovery, detailed mechanisms delineating the dynamic subcellular localization of its different componen...

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Vydáno v:Trends Biochem Sci
Hlavní autoři: Vashi, Nimi, Bakhoum, Samuel F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122033/
https://ncbi.nlm.nih.gov/pubmed/33461879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2020.12.010
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