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The evolution of STING signaling and its implication in cancer

The cGAS-STING pathway has been primarily characterized as an inflammatory response mechanism in higher eukaryotes in response to the presence of cytosolic double-stranded DNA. Since its initial discovery, detailed mechanisms delineating the dynamic subcellular localization of its different componen...

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Detalhes bibliográficos
Publicado no:Trends Biochem Sci
Main Authors: Vashi, Nimi, Bakhoum, Samuel F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122033/
https://ncbi.nlm.nih.gov/pubmed/33461879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2020.12.010
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