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cGAS-STING: insight on the evolution of a primordial antiviral signaling cassette
Stimulator of interferon genes (STING) functions in the cytosolic DNA-sensing pathway of innate immunity in mammals. It is activated upon binding the cyclic dinucleotide 2′3′-cGAMP, a second messenger produced by the enzyme cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS), whic...
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| Publicado en: | Fac Rev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Faculty Opinions Ltd
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204762/ https://ncbi.nlm.nih.gov/pubmed/34195693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12703/r/10-54 |
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