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Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments

Defining the principles of T cell migration in structurally and mechanically complex tumor microenvironments is critical to understanding escape from antitumor immunity and optimizing T cell-related therapeutic strategies. Here, we engineered nanotextured elastic platforms to study and enhance T cel...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Tabdanov, Erdem D., Rodríguez-Merced, Nelson J., Cartagena-Rivera, Alexander X., Puram, Vikram V., Callaway, Mackenzie K., Ensminger, Ethan A., Pomeroy, Emily J., Yamamoto, Kenta, Lahr, Walker S., Webber, Beau R., Moriarity, Branden S., Zhovmer, Alexander S., Provenzano, Paolo P.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121808/
https://ncbi.nlm.nih.gov/pubmed/33990566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22985-5
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