EditR: A Method to Quantify Base Editing from Sanger Sequencing

CRISPR-Cas9-Cytidine deaminase fusion enzymes—termed “base editors”—allow targeted editing of genomic deoxycytidine to deoxythymidine (C:G→T:A) without the need for double-stranded break induction. Base editors represent a paradigm shift in gene editing technology due to their unprecedented efficien...

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Bibliografiske detaljer
Udgivet i:CRISPR J
Main Authors: Kluesner, Mitchell G., Nedveck, Derek A., Lahr, Walker S., Garbe, John R., Abrahante, Juan E., Webber, Beau R., Moriarity, Branden S.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694769/
https://ncbi.nlm.nih.gov/pubmed/31021262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/crispr.2018.0014
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