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EditR: A Method to Quantify Base Editing from Sanger Sequencing
CRISPR-Cas9-Cytidine deaminase fusion enzymes—termed “base editors”—allow targeted editing of genomic deoxycytidine to deoxythymidine (C:G→T:A) without the need for double-stranded break induction. Base editors represent a paradigm shift in gene editing technology due to their unprecedented efficien...
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| Publicado no: | CRISPR J |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6694769/ https://ncbi.nlm.nih.gov/pubmed/31021262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/crispr.2018.0014 |
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