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Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes

Viral infection and pathogenesis is mediated by host protein—viral protein complexes that are important targets for therapeutic intervention as they are potentially less prone to development of drug resistance. We have identified human, recombinant antibodies (Fabs) from a phage display library that...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Sevillano, Natalia, Green, Evan M., Votteler, Jörg, Kim, Dong Young, Ren, Xuefeng, Yang, Bei, Liu, Xi, Lourenço, André Luiz, Hurley, James H., Farr-Jones, Shauna, Gross, John D., Cheng, Yifan, Craik, Charles S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8118348/
https://ncbi.nlm.nih.gov/pubmed/33983947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250318
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