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Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes

Viral infection and pathogenesis is mediated by host protein—viral protein complexes that are important targets for therapeutic intervention as they are potentially less prone to development of drug resistance. We have identified human, recombinant antibodies (Fabs) from a phage display library that...

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Publicado en:PLoS One
Autores principales: Sevillano, Natalia, Green, Evan M., Votteler, Jörg, Kim, Dong Young, Ren, Xuefeng, Yang, Bei, Liu, Xi, Lourenço, André Luiz, Hurley, James H., Farr-Jones, Shauna, Gross, John D., Cheng, Yifan, Craik, Charles S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8118348/
https://ncbi.nlm.nih.gov/pubmed/33983947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250318
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