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Dicarbonyl stress, protein glycation and the unfolded protein response

The reactive dicarbonyl metabolite, methylglyoxal (MG), is increased in obesity and diabetes and is implicated in the development of insulin resistance, type 2 diabetes mellitus and vascular complications of diabetes. Dicarbonyl stress is the metabolic state of abnormal high MG concentration. MG is...

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Detalhes bibliográficos
Publicado no:Glycoconj J
Main Authors: Rabbani, Naila, Xue, Mingzhan, Thornalley, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116241/
https://ncbi.nlm.nih.gov/pubmed/33644826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-021-09980-0
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