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Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal

Metabolic dysfunction of endothelial cells in hyperglycemia contributes to the development of vascular complications of diabetes where increased reactive glycating agent, methylglyoxal (MG), is involved. We assessed if increased MG glycation induced proteotoxic stress, identifying related metabolic...

Deskribapen osoa

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Irshad, Zehra, Xue, Mingzhan, Ashour, Amal, Larkin, James R., Thornalley, Paul J., Rabbani, Naila
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536510/
https://ncbi.nlm.nih.gov/pubmed/31133647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44358-1
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