Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer

INTRODUCTION: Patients with diabetes have increased risk of periodontal disease, with increased risk of weakening of periodontal ligament and tooth loss. Periodontal ligament is produced and maintained by periodontal ligament fibroblasts (PDLFs). We hypothesized that metabolic dysfunction of PDLFs i...

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Bibliografske podrobnosti
izdano v:BMJ Open Diabetes Res Care
Main Authors: Ashour, Amal, Xue, Mingzhan, Al-Motawa, Maryam, Thornalley, Paul J, Rabbani, Naila
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2020
Teme:
Pathophysiology/Complications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594206/
https://ncbi.nlm.nih.gov/pubmed/33115819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2020-001458
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