Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer

INTRODUCTION: Patients with diabetes have increased risk of periodontal disease, with increased risk of weakening of periodontal ligament and tooth loss. Periodontal ligament is produced and maintained by periodontal ligament fibroblasts (PDLFs). We hypothesized that metabolic dysfunction of PDLFs i...

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Detalles Bibliográficos
Publicado en:BMJ Open Diabetes Res Care
Autores principales: Ashour, Amal, Xue, Mingzhan, Al-Motawa, Maryam, Thornalley, Paul J, Rabbani, Naila
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2020
Materias:
Pathophysiology/Complications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594206/
https://ncbi.nlm.nih.gov/pubmed/33115819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2020-001458
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