Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer

INTRODUCTION: Patients with diabetes have increased risk of periodontal disease, with increased risk of weakening of periodontal ligament and tooth loss. Periodontal ligament is produced and maintained by periodontal ligament fibroblasts (PDLFs). We hypothesized that metabolic dysfunction of PDLFs i...

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Vydáno v:BMJ Open Diabetes Res Care
Hlavní autoři: Ashour, Amal, Xue, Mingzhan, Al-Motawa, Maryam, Thornalley, Paul J, Rabbani, Naila
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2020
Témata:
Pathophysiology/Complications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594206/
https://ncbi.nlm.nih.gov/pubmed/33115819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2020-001458
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