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Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress

Protection of mitochondrial proteins from glycation by endogenous dicarbonyl compounds, methylglyoxal and glyoxal, was found recently to prevent increased formation of reactive oxygen species and oxidative and nitrosative damage to the proteome during aging and produce life extension in the nematode...

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Detalhes bibliográficos
Main Authors: Rabbani, Naila, Thornalley, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639773/
https://ncbi.nlm.nih.gov/pubmed/18793186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0361045
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