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Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress
Protection of mitochondrial proteins from glycation by endogenous dicarbonyl compounds, methylglyoxal and glyoxal, was found recently to prevent increased formation of reactive oxygen species and oxidative and nitrosative damage to the proteome during aging and produce life extension in the nematode...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2639773/ https://ncbi.nlm.nih.gov/pubmed/18793186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0361045 |
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