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Preparation of Nucleotide Advanced Glycation Endproducts—Imidazopurinone Adducts Formed by Glycation of Deoxyguanosine with Glyoxal and Methylglyoxal

An analytical procedure was developed for nucleotide advanced glycation endproducts formed by the reaction of glyoxal and methylglyoxal with deoxyguanosine under physiological conditions. For this, the imidazopurinone derivatives, 3-(2′-deoxyribosyl)-6,7-dihydro-6,7-dihydroxyimidazo[2,3-b]purin-9(8)...

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Detalhes bibliográficos
Main Authors: Fleming, Thomas, Rabbani, Naila, Thornalley, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639770/
https://ncbi.nlm.nih.gov/pubmed/18448831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1433.037
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