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Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose.

The glycation of proteins by glucose has been linked to the development of diabetic complications and other diseases. Early glycation is thought to involve the reaction of glucose with N-terminal and lysyl side chain amino groups to form Schiff's base and fructosamine adducts. The formation of...

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Detalhes bibliográficos
Main Authors: Thornalley, P J, Langborg, A, Minhas, H S
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220620/
https://ncbi.nlm.nih.gov/pubmed/10548540
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