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Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose.

The glycation of proteins by glucose has been linked to the development of diabetic complications and other diseases. Early glycation is thought to involve the reaction of glucose with N-terminal and lysyl side chain amino groups to form Schiff's base and fructosamine adducts. The formation of...

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Библиографические подробности
Главные авторы: Thornalley, P J, Langborg, A, Minhas, H S
Формат: Artigo
Язык:Inglês
Опубликовано: 1999
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220620/
https://ncbi.nlm.nih.gov/pubmed/10548540
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