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Structure of the murine lysosomal multienzyme complex core

The enzymes β-galactosidase (GLB1) and neuraminidase 1 (NEU1; sialidase 1) participate in the degradation of glycoproteins and glycolipids in the lysosome. To remain active and stable, they associate with PPCA [protective protein cathepsin A (CTSA)] into a high–molecular weight lysosomal multienzyme...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Gorelik, Alexei, Illes, Katalin, Hasan, S. M. Naimul, Nagar, Bhushan, Mazhab-Jafari, Mohammad T.
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115914/
https://ncbi.nlm.nih.gov/pubmed/33980489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abf4155
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