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Identifying genetic modulators of statin response using subject-derived lymphoblastoid cell lines

Although statins (3-hydroxy-3-methylglutaryl-CoA reductase inhibitors) have proven effective in reducing plasma low-density lipoprotein levels and risk of cardiovascular disease, their lipid lowering efficacy is highly variable among individuals. Furthermore, statin treatment carries a small but sig...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Kuang, Yu-Lin, Theusch, Elizabeth, M Krauss, Ronald, W Medina, Marisa
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115385/
https://ncbi.nlm.nih.gov/pubmed/33858191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2020-0197
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