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Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines

BACKGROUND: Statins are widely prescribed to lower plasma low-density lipoprotein cholesterol levels. Though statins reduce cardiovascular disease risk overall, statin efficacy varies, and some people experience adverse side effects while on statin treatment. Statins also have pleiotropic effects no...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Theusch, Elizabeth, Chen, Yii-Der I., Rotter, Jerome I., Krauss, Ronald M., Medina, Marisa W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430882/
https://ncbi.nlm.nih.gov/pubmed/32787775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-06966-4
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