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Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines

BACKGROUND: Statins are widely prescribed to lower plasma low-density lipoprotein cholesterol levels. Though statins reduce cardiovascular disease risk overall, statin efficacy varies, and some people experience adverse side effects while on statin treatment. Statins also have pleiotropic effects no...

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Bibliografski detalji
Izdano u:BMC Genomics
Glavni autori: Theusch, Elizabeth, Chen, Yii-Der I., Rotter, Jerome I., Krauss, Ronald M., Medina, Marisa W.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430882/
https://ncbi.nlm.nih.gov/pubmed/32787775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-06966-4
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