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Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation
BACKGROUND: Statins are widely prescribed for lowering LDL-cholesterol (LDLC) levels and risk of cardiovascular disease. There is, however, substantial inter-individual variation in the magnitude of statin-induced LDLC reduction. To date, analysis of individual DNA sequence variants has explained on...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4180544/ https://ncbi.nlm.nih.gov/pubmed/25316374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0460-9 |
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