RHOA Is a Modulator of the Cholesterol-Lowering Effects of Statin

Although statin drugs are generally efficacious for lowering plasma LDL-cholesterol levels, there is considerable variability in response. To identify candidate genes that may contribute to this variation, we used an unbiased genome-wide filter approach that was applied to 10,149 genes expressed in...

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Autors principals: Medina, Marisa W., Theusch, Elizabeth, Naidoo, Devesh, Bauzon, Frederick, Stevens, Kristen, Mangravite, Lara M., Kuang, Yu-Lin, Krauss, Ronald M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499361/
https://ncbi.nlm.nih.gov/pubmed/23166513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003058
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