Lataa...
HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism
3-hydroxy-3-methylglutaryl-Coenzyme A reductase (HMGCR) encodes the rate-limiting enzyme in the cholesterol biosynthesis pathway and is inhibited by statins, a class of cholesterol-lowering drugs. Expression of an alternatively spliced HMGCR transcript lacking exon 13, HMGCR13(−), has been implicate...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2014
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869353/ https://ncbi.nlm.nih.gov/pubmed/24001602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt422 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|