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Molecular, functional, and pathological aspects of TDP-43 fragmentation
Transactive response DNA binding protein 43 (TDP-43) is a DNA/RNA binding protein involved in transcriptional regulation and RNA processing. It is linked to sporadic and familial amyotrophic lateral sclerosis and frontotemporal lobar degeneration. TDP-43 is predominantly nuclear, but it translocates...
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| Veröffentlicht in: | iScience |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8113996/ https://ncbi.nlm.nih.gov/pubmed/34013172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102459 |
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