Molecular properties of human guanylate cyclase–activating protein 2 (GCAP2) and its retinal dystrophy–associated variant G157R

In murine and bovine photoreceptors, guanylate cyclase–activating protein 2 (GCAP2) activates retinal guanylate cyclases (GCs) at low Ca(2+) levels, thus contributing to the Ca(2+)/cGMP negative feedback on the cyclase together with its paralog guanylate cyclase–activating protein 1, which has the s...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Avesani, Anna, Marino, Valerio, Zanzoni, Serena, Koch, Karl-Wilhelm, Dell'Orco, Daniele
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2021
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113879/
https://ncbi.nlm.nih.gov/pubmed/33812995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100619
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items