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Structural Insights for Activation of Retinal Guanylate Cyclase by GCAP1

Guanylyl cyclase activating protein 1 (GCAP1), a member of the neuronal calcium sensor (NCS) subclass of the calmodulin superfamily, confers Ca(2+)-sensitive activation of retinal guanylyl cyclase 1 (RetGC1) upon light activation of photoreceptor cells. Here we present NMR assignments and functional...

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Autors principals: Lim, Sunghyuk, Peshenko, Igor V., Dizhoor, Alexander M., Ames, James B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827477/
https://ncbi.nlm.nih.gov/pubmed/24236217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081822
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