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Autophagy mediated lipid catabolism facilitates glioma progression to overcome bioenergetic crisis

BACKGROUND: Activation of mTORC1 plays a significant role in cancer development and progression. However, the metabolic mechanisms to sustain mTORC1 activation of cancer cells within stressed environments are still under-appreciated. We recently revealed high autophagy activity in tumour cells with...

詳細記述

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書誌詳細
出版年:Br J Cancer
主要な著者: Wang, Chenran, Haas, Michael A., Yeo, Syn Kok, Paul, Ritama, Yang, Fuchun, Vallabhapurapu, Subrahmanya, Qi, Xiaoyang, Plas, David R., Guan, Jun-Lin
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8110959/
https://ncbi.nlm.nih.gov/pubmed/33723393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-021-01294-0
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