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Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer

Breast cancer is a heterogeneous disease, and stratification of patients is fundamental to the success of treatment modalities. Breast tumors deficient in BRCA1 are mostly associated with basal-like breast cancers and targeted therapeutics for this disease subtype are still lacking. In order to addr...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Yeo, Syn Kok, Paul, Ritama, Haas, Michael, Wang, Chenran, Guan, Jun-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103709/
https://ncbi.nlm.nih.gov/pubmed/29938573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1460010
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