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Phe-Gly motifs drive fibrillization of TDP-43’s prion-like domain condensates
Transactive response DNA-binding Protein of 43 kDa (TDP-43) assembles various aggregate forms, including biomolecular condensates or functional and pathological amyloids, with roles in disparate scenarios (e.g., muscle regeneration versus neurodegeneration). The link between condensates and fibrils...
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| Publié dans: | PLoS Biol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8109789/ https://ncbi.nlm.nih.gov/pubmed/33909608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001198 |
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