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Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo

The cytokine RANKL is essential for osteoclast formation during physiological and pathological bone resorption. RANKL also contributes to lymphocyte production, development of lymph nodes and mammary glands, as well as other biological activities. Transcriptional control of the Tnfsf11 gene, which e...

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Publicado en:PLoS One
Autores principales: MacLeod, Ryan S., Meyer, Mark B., Xiong, Jinhu, Cawley, Keisha M., Liu, Yu, Onal, Melda, Benkusky, Nancy A., Thostenson, Jeff D., Pike, J. Wesley, O’Brien, Charles A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109787/
https://ncbi.nlm.nih.gov/pubmed/33970941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250974
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