A DNA Segment Spanning the Mouse Tnfsf11 Transcription Unit and Its Upstream Regulatory Domain Rescues the Pleiotropic Biologic Phenotype of the RANKL Null Mouse

Receptor activator of NF-κB ligand (RANKL) is a TNFα-like cytokine that is produced by a diverse set of lineage-specific cells and is involved in a wide variety of physiological processes that include skeletal remodeling, lymph node organogenesis, mammary gland development, and thermal regulation. C...

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Publicado en:J Bone Miner Res
Main Authors: Onal, Melda, Bishop, Kathleen A, St. John, Hillary C, Danielson, Allison L, Riley, Erin M, Piemontese, Marilina, Xiong, Jinhu, Goellner, Joseph J, O’Brien, Charles A, Pike, J Wesley
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240630/
https://ncbi.nlm.nih.gov/pubmed/25431114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2417
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