Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo

The cytokine RANKL is essential for osteoclast formation during physiological and pathological bone resorption. RANKL also contributes to lymphocyte production, development of lymph nodes and mammary glands, as well as other biological activities. Transcriptional control of the Tnfsf11 gene, which e...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: MacLeod, Ryan S., Meyer, Mark B., Xiong, Jinhu, Cawley, Keisha M., Liu, Yu, Onal, Melda, Benkusky, Nancy A., Thostenson, Jeff D., Pike, J. Wesley, O’Brien, Charles A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109787/
https://ncbi.nlm.nih.gov/pubmed/33970941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250974
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