Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo

The cytokine RANKL is essential for osteoclast formation during physiological and pathological bone resorption. RANKL also contributes to lymphocyte production, development of lymph nodes and mammary glands, as well as other biological activities. Transcriptional control of the Tnfsf11 gene, which e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: MacLeod, Ryan S., Meyer, Mark B., Xiong, Jinhu, Cawley, Keisha M., Liu, Yu, Onal, Melda, Benkusky, Nancy A., Thostenson, Jeff D., Pike, J. Wesley, O’Brien, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109787/
https://ncbi.nlm.nih.gov/pubmed/33970941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250974
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