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Molecular mechanisms underlying cellular effects of human MEK1 mutations

Terminal regions of Drosophila embryos are patterned by signaling through ERK, which is genetically deregulated in multiple human diseases. Quantitative studies of terminal patterning have been recently used to investigate gain-of-function variants of human MEK1, encoding the MEK kinase that directl...

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Bibliografiska uppgifter
I publikationen:Mol Biol Cell
Huvudupphovsmän: Marmion, Robert A., Yang, Liu, Goyal, Yogesh, Jindal, Granton A., Wetzel, Joshua L., Singh, Mona, Schüpbach, Trudi, Shvartsman, Stanislav Y.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2021
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108529/
https://ncbi.nlm.nih.gov/pubmed/33476180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-10-0625
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