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Molecular mechanisms underlying cellular effects of human MEK1 mutations
Terminal regions of Drosophila embryos are patterned by signaling through ERK, which is genetically deregulated in multiple human diseases. Quantitative studies of terminal patterning have been recently used to investigate gain-of-function variants of human MEK1, encoding the MEK kinase that directl...
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| Publicado no: | Mol Biol Cell |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8108529/ https://ncbi.nlm.nih.gov/pubmed/33476180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-10-0625 |
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