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RASopathies: unraveling mechanisms with animal models
RASopathies are developmental disorders caused by germline mutations in the Ras-MAPK pathway, and are characterized by a broad spectrum of functional and morphological abnormalities. The high incidence of these disorders (∼1/1000 births) motivates the development of systematic approaches for their e...
Gespeichert in:
| Veröffentlicht in: | Dis Model Mech |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527292/ https://ncbi.nlm.nih.gov/pubmed/26203125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020339 |
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