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WNT/β-catenin-suppressed FTO expression increases m(6)A of c-Myc mRNA to promote tumor cell glycolysis and tumorigenesis
FTO removes the N6-methyladenosine (m(6)A) modification from genes and plays a critical role in cancer development. However, the mechanisms underlying the regulation of FTO and its subsequent impact on the regulation of the epitranscriptome remain to be further elucidated. Here, we demonstrate that...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8106678/ https://ncbi.nlm.nih.gov/pubmed/33966037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03739-z |
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