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A Sos proteomimetic as a pan-Ras inhibitor
Aberrant Ras signaling is linked to a wide spectrum of hyperproliferative diseases, and components of the signaling pathway, including Ras, have been the subject of intense and ongoing drug discovery efforts. The cellular activity of Ras is modulated by its association with the guanine nucleotide ex...
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| Τόπος έκδοσης: | Proc Natl Acad Sci U S A |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8106295/ https://ncbi.nlm.nih.gov/pubmed/33926964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2101027118 |
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