Lycopene alleviates hepatic ischemia reperfusion injury via the Nrf2/HO-1 pathway mediated NLRP3 inflammasome inhibition in Kupffer cells

BACKGROUND: Lycopene is a naturally occurring carotenoid found in many fruits and vegetables, which has antioxidant effects. Although lycopene’s protective effect has been observed on ischemia reperfusion (IR) injury in different organs, the effect of lycopene on Kupffer cells (KCs) has not been cle...

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Veröffentlicht in:Ann Transl Med
Hauptverfasser: Xue, Rong, Qiu, Jiannan, Wei, Song, Liu, Mu, Wang, Qi, Wang, Peng, Sha, Bowen, Wang, Hao, Shi, Yong, Zhou, Jinren, Rao, Jianhua, Lu, Ling
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2021
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106004/
https://ncbi.nlm.nih.gov/pubmed/33987329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-7084
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