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Ulinastatin alleviates cerebral ischemia-reperfusion injury in rats by activating the Nrf-2/HO-1 signaling pathway

BACKGROUND: Ulinastatin, a urinary trypsin inhibitor, is one of the widely used auxiliary drugs in the rescue of acute circulatory failure. This study aims to explore the protective mechanisms of ulinastatin on cerebral ischemia-reperfusion (I/R) injury. METHODS: A cerebral MCAO was established with...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Cui, Lei, Cao, Wei, Xia, Yanmin, Li, Xiaofang
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576027/
https://ncbi.nlm.nih.gov/pubmed/33240985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5115
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