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Mechanistic link between CaM-RyR2 interactions and the genesis of cardiac arrhythmia

In this study, we develop a computational model of the interaction between ryanodine receptor type 2 (RyR2) and calmodulin (CaM) to explore the mechanistic link between CaM-RyR2 interactions and cardiac arrhythmia. Our starting point is a biophysically based computational model of CaM binding to a s...

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Vydáno v:Biophys J
Hlavní autoři: Greene, D’Artagnan, Shiferaw, Yohannes
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105736/
https://ncbi.nlm.nih.gov/pubmed/33617831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.02.016
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