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Structure Property Relationships of N-Acylsulfonamides and Related Bioisosteres

The N-acylsulfonamide functional group is a feature of the pharmacophore of several biologically active molecules, including marketed drugs. Although this acidic moiety presents multiple point of attachments that could be exploited to introduce structural diversification, depending on the circumstan...

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Dades bibliogràfiques
Publicat a:Eur J Med Chem
Autors principals: Francisco, Karol R., Varricchio, Carmine, Paniak, Thomas J., Kozlowski, Marisa C., Brancale, Andrea, Ballatore, Carlo
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105289/
https://ncbi.nlm.nih.gov/pubmed/33823393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2021.113399
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