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Endothelial Rap1 restricts inflammatory signaling to protect from the progression of atherosclerosis.

OBJECTIVE: Small GTPase Rap1 is a novel, positive regulator of NO release and endothelial function with a potentially key role in mechanosensing of atheroprotective, laminar flow. Our objective was to delineate the role of Rap1 in the progression of atherosclerosis and its specific functions in the...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Singh, Bandana, Kosuru, Ramoji, Lakshmikanthan, Sribalaji, Sorci-Thomas, Mary, Zhang, David, Sparapani, Rodney, Vasquez-Vivar, Jeannette, Chrzanowska, Magdalena
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105264/
https://ncbi.nlm.nih.gov/pubmed/33267664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315401
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