De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma

Glioblastoma is a primary brain cancer with a near 100% recurrence rate. Upon recurrence, the tumour is resistant to all conventional therapies, and because of this, 5-year survival is dismal. One of the major drivers of this high recurrence rate is the ability of glioblastoma cells to adapt to comp...

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Spremljeno u:
Bibliografski detalji
Izdano u:Brain
Glavni autori: Shireman, Jack M, Atashi, Fatemeh, Lee, Gina, Ali, Eunus S, Saathoff, Miranda R, Park, Cheol H, Savchuk, Sol, Baisiwala, Shivani, Miska, Jason, Lesniak, Maciej S, James, C David, Stupp, Roger, Kumthekar, Priya, Horbinski, Craig M, Ben-Sahra, Issam, Ahmed, Atique U
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105035/
https://ncbi.nlm.nih.gov/pubmed/33855339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awab020
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