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DRES-09. REGULATORY EFFECTS OF THE CILIARY GTPASE ARL13B ON PURINE METABOLISM IN GBM

Glioblastoma (GBM) is the most common form of adult primary brain cancer. Despite an aggressive treatment regimen – surgical resection, irradiation, and temozolomide (TMZ) chemotherapy – patients’ prognosis is still grim. TMZ acts by methylating purines, specifically at the O6 and N7 positions of gu...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Saathoff, Miranda, Shireman, Jack, Ali, Eunus, Park, Cheol, Ben-Sahra, Issam, Ahmed, Atique
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847615/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.297
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