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DDRE-27. LMNA-PRKDC AXIS PROMOTES CHEMORESISTANCE IN RECURRENT GBM BY STABILIZING DNA REPAIR FOCI

Tumors in patients with recurrent GBM are resistant to standard therapies. Available models for testing experimental therapies to treat GBM are primarily derived from or representative of primary, untreated GBM. We have developed a clinically relevant model of recurrent, therapy-resistant glioblasto...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Saathoff, Miranda, Shireman, Jack, Savchuk, Sol, Baisiwala, Shivani, Park, Cheol, James, Charles, Ahmed, Atique
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651234/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.272
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